Wegovy vs Saxenda
Comparing the two leading GLP-1 weight loss medications from Novo Nordisk.
| Feature | Wegovy | Saxenda |
|---|---|---|
| Active Ingredient | Semaglutide | Liraglutide |
| Mechanism | GLP-1 Agonist | GLP-1 Agonist |
| Avg Weight Loss | Up to 15% | Up to 8% |
| Frequency | Weekly | Daily |
| Starting Price | ~$249 | ~$89 |
Evolution of Treatment
Saxenda (Liraglutide) was the first GLP-1 agonist approved for weight loss. It requires a daily injection. Wegovy (Semaglutide) is the newer generation, requiring only a weekly injection and demonstrating significantly higher weight loss efficacy in clinical trials.
Many patients start on Saxenda and switch to Wegovy for the convenience of weekly dosing and better results. However, Saxenda remains a valid option, especially for those who may be sensitive to side effects, as the daily dose clears from the system faster if stopped.
Price vs Value
While Saxenda may have a lower "starting price" per pen, the daily usage means you go through more pens. Wegovy is generally considered more cost-effective when measuring price per percentage of weight lost.
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